About two-thirds of young patients with type 1 diabetes may have skin disorders.
Skin manifestations generally appear subsequent to the development
of diabetes but may be the first presenting sign or even precede the
diagnosis by many years.
A study of the Military Medical Academy compared the presence and
frequency of skin manifestations in 212 unselected patients with type 1
diabetes ranging in age from 2 to 22 years (diabetes duration 1 to 15
years) and 196 healthy matched control subjects.
Overall, 142 (67%) diabetic patients had at least one skin
disorder versus 52 (26%) control subjects (p < 0.01). Skin lesions
that were considered to be associated with diabetes were observed in 81
patients (38%).
Xerosis was found in 22% of patients with type 1 diabetes and 3%
of controls. Rubeosis, diabetic hand, and necrobiosis lipoidica were
found in 7.1%, 2.3%, and 2.3% of diabetics, respectively. None of the
control subjects experienced these skin manifestations.
The study concludes that the frequency and range of skin lesions
justify the early inclusion of a dermatologist in the management of
type 1 diabetic patients.
Source: Diabetes Care 2007;30:1964-1967.